Which of the following is a key feature of diabetes mellitus Type 2?

The key feature of Type 2 diabetes mellitus is insulin resistance. In this condition, the body's cells do not respond effectively to insulin, which is a hormone that helps regulate blood glucose levels. As a result, the pancreas produces more insulin to help achieve the necessary glucose uptake by the cells. Over time, this compensatory mechanism fails, leading to elevated blood glucose levels.

In addition to insulin resistance, Type 2 diabetes is often associated with obesity, sedentary lifestyle, and varying degrees of genetic predisposition. This combination increases the likelihood of developing insulin resistance, contributing to the chronic nature of the disease.

In contrast, autoimmune destruction of beta cells is a hallmark of Type 1 diabetes and not relevant to Type 2 diabetes. Low blood pressure is not a defining feature of diabetes and has no direct correlation with the condition. While high insulin production may occur as a response to insulin resistance, it does not define Type 2 diabetes as a key feature; rather, it is a consequence of the body's attempt to overcome the resistance. Thus, insulin resistance stands out as the primary characteristic of Type 2 diabetes mellitus.